Author

Zuoshang Xu

University of Massachusetts Chan Medical SchoolORCID 0000-0003-1209-334XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Issa Olakunle YusufiD· 3 shared Albino BacollaiD· 1 shared Chunxing Yang· 1 shared Gavin Wayne BritziD· 1 shared George G Amoako· 1 shared Guo‐Min LiiD· 1 shared Hongyan WangiD· 1 shared Huaibin CaiiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersNeuroscience

Issa Olakunle YusufORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintJun 3, 2026

PAD2 knockout reduces myelin protein aggregates, modulates neuroinflammation and protects motor neurons, axons and neuromuscular junction in a SOD1-ALS mouse model

Issa Olakunle Yusuf, Rogerio L.A. Silva, George G Amoako…·Zuoshang Xu

This study shows that PAD2 knockout reduces protein citrullination, improves motor neuron and axon integrity, and modulates neuroinflammation in a SOD1-ALS mouse model.

DOI 10.64898/2026.05.30.729013

mousestatistical model

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NeuroscienceNucleic Acids ResearchPeer-reviewedSep 23, 2025

RNA/DNA Binding Protein TDP43 Regulates DNA Mismatch Repair Genes with Implications for Genome Stability

Vincent E. Provasek, Albino Bacolla, Suganya Rangaswamy…·Muralidhar L. Hegde

This study shows TDP43 regulates DNA mismatch repair genes, affecting genome stability in neurodegenerative and cancer contexts.

13 citationstop 4%

humanmouse

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GeneticsPLoS ONEPeer-reviewedFeb 3, 2022

Low-level overexpression of wild type TDP-43 causes late-onset, progressive neurodegeneration and paralysis in mice

Chunxing Yang, Tao Qiao, Jia Hui Yu…·Zuoshang Xu

This study shows that low-level overexpression of wild-type TDP-43 in mice causes late-onset, progressive neurodegeneration and paralysis, mimicking aspects of ALS and other TDP-43-related disorders.

57 citationstop 2%

mouseexperimental assay

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