Synthetic BiologybioRxivPreprint
Escherichia coli adapts metabolically to 6- and 7-fluoroindole, enabling proteome-wide fluorotryptophan substitution
Christin Treiber-Kleinke, Allison Berger, Lorenz Adrian…·Beate Koksch
This study evolves Escherichia coli to use fluorinated indoles as nutrients, converting them into fluorotryptophan and incorporating them into the proteome.
DOI 10.1101/2023.09.25.559291