Author

Christin Treiber-Kleinke

Freie Universität BerlinORCID 0009-0002-6924-5236Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:experimental assay· 2 Assay:proteomics· 1

Frequent Co-Authors

Nediljko BudišaiD· 2 shared Abdul-Rahman Adamu BukariiD· 1 shared Aleeza C. GersteiniD· 1 shared Allison BergeriD· 1 shared Beate KokschiD· 1 shared Isabella TolleiD· 1 shared Juri RappsilberiD· 1 shared Lauri PeiliD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersSynthetic Biology

Nediljko BudišaORCID

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2 papers

Recent·Most cited

Escherichia coli adapts metabolically to 6- and 7-fluoroindole, enabling proteome-wide fluorotryptophan substitution

Christin Treiber-Kleinke, Allison Berger, Lorenz Adrian, Nediljko Budiša, Beate Koksch

This study evolves Escherichia coli to use fluorinated indoles as nutrients, converting them into fluorotryptophan and incorporating them into the proteome.

bioRxiv · Sep 25, 2023 · PreprintSynthetic Biology

Evolving a mitigation of the stress response pathway to change the basic chemistry of life

Isabella Tolle, Stefan Oehm, Michael Georg Hoesl, Christin Treiber-Kleinke, Lauri Peil, Mihaela Bozukova, Suki Albers, Abdul-Rahman Adamu Bukari, Torsten Semmler, Juri Rappsilber, Zoya Ignatova, Aleeza C. Gerstein, Nediljko Budiša

This paper uses adaptive laboratory evolution to replace tryptophan in E. coli with a synthetic analog, revealing that stress response inhibition, not translation rigidity, limits genetic code expansion.

Frontiers in Synthetic Biology · Aug 24, 2023Peer-reviewedSynthetic Biology