Rachel M. Lukowicz-Bedford

Electrical synapse molecular diversity revealed by proximity-based proteomic discovery

The paper identifies hundreds of Connexin-associated proteins in zebrafish electrical synapses, revealing molecular diversity and overlap with chemical synapse proteomes, and links these proteins to neurological disorders.

Gap junction mediated bioelectric coordination is required for slow muscle development, organization, and function

The paper identifies gjd4/Cx46.8 as a gap junction protein essential for bioelectric signaling in zebrafish slow muscle development and function, showing its role in coordinating neural and muscular activity.

Electrical synapse formation is differentially regulated by distinct isoforms of a postsynaptic scaffold

The paper shows that different isoforms of the ZO1b gene contribute uniquely to the electrical synapse density complex, affecting gap junction channel localization and function in zebrafish.

Connexinplexity: The spatial and temporal expression of connexin genes during vertebrate organogenesis

The paper maps the spatial and temporal expression of connexin genes in zebrafish during organogenesis, revealing tissue- and cell-type-specific patterns and providing a guide for human connexin genes.