Author

Julien L. P. Morival

University of California, IrvineORCID 0000-0003-1252-025XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1

Frequent Co-Authors

Elizabeth L. ReadiD· 2 shared Timothy L. DowningiD· 2 shared Alexander A. GimelbrantiD· 1 shared Annie TrinhiD· 1 shared Arjang FahimiD· 1 shared Asia MendelevichiD· 1 shared Honglei ReniD· 1 shared Ioannis NtekasiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersGenomics

Elizabeth L. ReadORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintMar 3, 2025

Methylation pseudotime analysis for label-free profiling of the temporal chromatin landscape with long-read sequencing

Annie Trinh, Navied Akhtar, Kwadwo Bonsu…·Timothy L. Downing

This paper introduces MPATH, a method to temporally order epigenetic modifications using long-read sequencing, revealing sub-cell-cycle dynamics of methylation states and nucleosome occupancy.

DOI 10.1101/2025.03.03.641287

long-read sequencingDNA methylation

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Cell BiologybioRxivPreprintJun 11, 2024

Nuclear envelope rupture in cardiomyocytes orchestrates early transcriptomic changes and immune activation in LMNA-related dilated cardiomyopathy that are reversed by LINC complex disruption

Noam Zuela-Sopilniak, Julien L. P. Morival, Ioannis Ntekas…·Jan Lammerding

This study identifies NE rupture in LMNA-DCM cardiomyocytes as a driver of transcriptomic changes and immune activation, which can be reversed by LINC complex disruption.

8 citations

mousebulk RNA-seq

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GenomicsPLoS Computational BiologyPeer-reviewedApr 10, 2020

Stochastic Modeling Reveals Kinetic Heterogeneity in Post-replication DNA Methylation

Luis Busto‐Moner, Julien L. P. Morival, Honglei Ren…·Elizabeth L. Read

The paper uses statistical and stochastic modeling to analyze Repli-BS data from human embryonic stem cells, revealing kinetic heterogeneity in post-replication DNA methylation.

31 citations

humanDNA methylation

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