GenomicsEpigeneticsPeer-reviewed
Ultra-deep whole genome bisulfite sequencing reveals a single methylation hotspot in human brain mitochondrial DNA
Romain Guitton, Christian Dölle, Guido Werner Alves…·Charalampos Tzoulis
This study uses ultra-deep whole genome bisulfite sequencing to analyze mtDNA methylation in human brain tissue, identifying a single CpG site with significant methylation and correlating it with mtDNA transcript levels.
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