Author
Haukeland University HospitalORCID 0000-0003-2427-8130Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Simon Ulvenes Kverneng, Kjersti Eline Stige, Haakon Berven…·Charalampos Tzoulis
The paper investigates mitochondrial complex I deficiency in Parkinson's disease muscle biopsies, finding 9% of cases show reduced CI activity without mtDNA abnormalities.
Irene Hana Flønes, Lilah Toker, Dagny Ann Sandnes…·Charalampos Tzoulis
This study identifies two subtypes of idiopathic Parkinson's disease based on mitochondrial complex I deficiency, with distinct molecular and clinical features.
Romain Guitton, Christian Dölle, Guido Werner Alves…·Charalampos Tzoulis
This study uses ultra-deep whole genome bisulfite sequencing to analyze mtDNA methylation in human brain tissue, identifying a single CpG site with significant methylation and correlating it with mtDNA transcript levels.
Lilah Toker, Gia Tuong Tran, Janani Sundaresan…·Charalampos Tzoulis
The paper identifies genome-wide dysregulation of histone acetylation in Parkinson's disease brains, linking it to disease-related genes and altered gene expression.