Author
University of California, San FranciscoORCID 0000-0003-1258-0391Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Lorraine Nuniz, Julia H. Pham, Juliette Jacques…·Franklin W. Huang
This study identifies TM4SF1 as a tumor-associated antigen in biliary tract cancers and shows anti-TM4SF1 CAR-T cells inhibit tumor growth in vitro and in vivo.
Haolong Li, James E. Melnyk, Becky Xu Hua Fu…·Felix Yi-Chung Feng
This study uses CRISPR screens to identify PTGES3 as a novel modulator of AR protein levels and function in prostate cancer, showing its role in therapy resistance.
Heiko Yang, Hanbing Song, Elizabeth Yip…·Franklin W. Huang
Single cell RNA sequencing of bladder cancer subtypes identified a CA125+ cell state linked to aggressive features and TM4SF1 as a therapeutic target.
Hui Li, Noah Spector Younger, Bhavna Malik…·Haolong Li
This study identifies PCAHIT, a lncRNA linked to poor outcomes in prostate cancer, showing it promotes aggressive phenotypes by affecting steroid biosynthesis and immune response.
Jean Ching-Yi Tien, Jie Luo, Yu Chang…·Arul M. Chinnaiyan
This study shows CDK12 loss drives prostate cancer development and identifies CDK13 as a therapeutic target through paralog-based synthetic lethality in CDK12-mutant tumors.