Ágnes Tantos

The paper identifies positive selection in human proteins, showing PSRs are enriched in extracellular regions and interaction interfaces, and links them to pathogen targeting and drug targets.

The paper analyzes flanking regions of short linear motifs to identify amino acid attributes that may enhance binding specificity and strength.

The paper evaluates 43 methods for predicting intrinsically disordered regions and binding regions in proteins, finding that deep learning methods outperform older physicochemical approaches but binding prediction remains challenging.

The paper introduces a method to study liquid-liquid phase separation under near-native conditions by using extreme pH to control protein solubility and induce phase separation.