Author

Helayne Soares Freitas

Universidade de São PauloORCID 0000-0003-1297-063XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Álbert S. PeixotoiD· 2 shared Ana B. PiresiD· 2 shared Ana Carolina P Baptista· 2 shared Bianca Franco LeonardiiD· 2 shared Camila Nogueira Alves BezerraiD· 2 shared Érika Vicência Monteiro PessoaiD· 2 shared Érique CastroiD· 2 shared Loreana Sanches SilveiraiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Álbert S. PeixotoORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintJun 23, 2026

Severely lipoatrophic mice are hypermetabolic and hyperthermic under thermoneutral conditions in part due to an enhanced liver de novo lipogenesis

Álbert S. Peixoto, Caroline Antunes Lino, Bianca Franco Leonardi…·William T. Festuccia

This study shows that severely lipoatrophic mice are hypermetabolic and hyperthermic at 30°C due to enhanced liver de novo lipogenesis, independent of thyroid hormones or calcium cycling.

DOI 10.64898/2026.06.18.733153

mouseexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintJun 18, 2026

Hepatocyte-, but not myeloid cell-Rictor/mTORC2 deficiency moderately attenuates steatotic liver disease induced by intake of a choline-deficient, amino acid-defined high-fat diet

Bianca Franco Leonardi, Ana B. Pires, Marina A. Abe‐Honda…·William T. Festuccia

This study shows that hepatocyte-specific mTORC2 deficiency slightly reduces liver disease from a choline-deficient diet, while myeloid cell deficiency has no effect.

DOI 10.64898/2026.06.17.732842

mouseexperimental assay

𝕏 PostBluesky