Author

Loreana Sanches Silveira

Universidade de São PauloORCID 0000-0003-4429-0153Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Álbert S. PeixotoiD· 2 shared Ana B. PiresiD· 2 shared Ana Carolina P Baptista· 2 shared Bianca Franco LeonardiiD· 2 shared Camila Nogueira Alves BezerraiD· 2 shared Érika Vicência Monteiro PessoaiD· 2 shared Érique CastroiD· 2 shared Helayne Soares FreitasiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Álbert S. PeixotoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

PhysiologybioRxivPreprintJun 23, 2026

Severely lipoatrophic mice are hypermetabolic and hyperthermic under thermoneutral conditions in part due to an enhanced liver de novo lipogenesis

Álbert S. Peixoto, Caroline Antunes Lino, Bianca Franco Leonardi…·William T. Festuccia

This study shows that severely lipoatrophic mice are hypermetabolic and hyperthermic at 30°C due to enhanced liver de novo lipogenesis, independent of thyroid hormones or calcium cycling.

DOI 10.64898/2026.06.18.733153

mouseexperimental assay

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BiochemistrybioRxivPreprintJun 18, 2026

Hepatocyte-, but not myeloid cell-Rictor/mTORC2 deficiency moderately attenuates steatotic liver disease induced by intake of a choline-deficient, amino acid-defined high-fat diet

Bianca Franco Leonardi, Ana B. Pires, Marina A. Abe‐Honda…·William T. Festuccia

This study shows that hepatocyte-specific mTORC2 deficiency slightly reduces liver disease from a choline-deficient diet, while myeloid cell deficiency has no effect.

DOI 10.64898/2026.06.17.732842

mouseexperimental assay

𝕏 PostBluesky

PhysiologyNature CommunicationsPeer-reviewedMay 31, 2025

MACanalyzeR: scRNA-seq Analysis Tool Reveals PPARγHI Lipid-Associated Macrophages Facilitate Thermogenic Expansion in BAT

Andrea Ninni, Fabio Zaccaria, Luca Verteramo…·Daniele Lettieri‐Barbato

The paper introduces MACanalyzeR, a scRNA-seq tool, to identify PPARγ-high lipid-associated macrophages in BAT that support thermogenic expansion.

11 citationstop 3%

mousescRNA-seq

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