Bassam G. Haddad

This study uses cryo-EM to reveal how calcium binding to connexin-46/50 gap junctions induces structural changes leading to pore collapse and gating.

This study uses computational simulations to reveal ion permeation mechanisms and dynamic conductance modulation in gap junction channels formed by connexin proteins.

This study identifies SLC26A11 as a dual-function protein that acts as both a sulfate transporter and a chloride channel, with implications for treating brain edema and lysosomal storage diseases.