Author

David W. Speicher

The Wistar InstituteORCID 0000-0003-1311-4261Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:protein structure prediction· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Hsin‐Yao TangiD· 2 shared Andreas WiedmeriD· 1 shared Ekapol ChuangsuwanichiD· 1 shared Jayaraju Dheekollu· 1 shared Korrawe KarunratanakuliD· 1 shared Leonardo Josué Castro-MuñoziD· 1 shared Paul M. LiebermaniD· 1 shared Samantha S. SoldaniD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Hsin‐Yao TangORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMar 29, 2022

Regulation of EBNA1 Protein Stability by PLOD1 Lysine Hydroxylase

Jayaraju Dheekollu, Andreas Wiedmer, Samantha S. Soldan…·Paul M. Lieberman

This study identifies PLOD1 as a post-translational regulator of EBNA1 protein stability and function in EBV latency, showing that PLOD1 depletion reduces EBNA1 levels and inhibits viral replication and episome maintenance.

DOI 10.1101/2022.03.29.486189

humanproteomics

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BioinformaticsbioRxivPreprintJun 11, 2019

Uncovering thousands of new HLA antigens and phosphopeptides with deep learning-based sequence-mask-search de novo peptide sequencing framework

Korrawe Karunratanakul, Hsin‐Yao Tang, David W. Speicher…·Sira Sriswasdi

The paper introduces SMSNet, a deep learning framework for de novo peptide sequencing that identifies thousands of new HLA antigens and phosphopeptides with high accuracy.

2 citations

proteomicsdeep learning

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