Author

Jayaraju Dheekollu

The Wistar Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Paul M. LiebermaniD· 2 shared Andreas WiedmeriD· 1 shared Asher A. Sobotka· 1 shared Asim Asghar· 1 shared David W. SpeicheriD· 1 shared Hsin‐Yao TangiD· 1 shared James E. HaydeniD· 1 shared Jayamanna M. Wickramasinghe· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Paul M. LiebermanORCID

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2 papers

Recent·Most cited

LANA-Dependent Transcription-Replication Conflicts and R-Loops at the Terminal Repeats (TR) Correlate with KSHV Episome Maintenance

Asim Asghar, Olga V. Vladimirova, Asher A. Sobotka, James E. Hayden, Jayamanna M. Wickramasinghe, Jayaraju Dheekollu, Moeko Minakuchi, Leena Yoon, Maureen E. Murphy, Kazuko Nishikura, Paul M. Lieberman

The paper shows LANA binding at KSHV TRs causes R-loops and histone modifications linked to episome maintenance.

PLoS Pathogens · Aug 18, 2025Peer-reviewedMolecular Biology

Regulation of EBNA1 Protein Stability by PLOD1 Lysine Hydroxylase

Jayaraju Dheekollu, Andreas Wiedmer, Samantha S. Soldan, Leonardo Josué Castro-Muñoz, Hsin‐Yao Tang, David W. Speicher, Paul M. Lieberman

This study identifies PLOD1 as a post-translational regulator of EBNA1 protein stability and function in EBV latency, showing that PLOD1 depletion reduces EBNA1 levels and inhibits viral replication and episome maintenance.

bioRxiv · Mar 29, 2022 · PreprintMolecular Biology