Author

Zhuyu Peng

Massachusetts Institute of TechnologyORCID 0000-0003-1327-4337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:deconvolution· 1

Frequent Co-Authors

Li‐Huei TsaiiD· 4 shared David A. A BennettiD· 3 shared M KellisiD· 3 shared Carles A. BoixiD· 2 shared Hansruedi MathysiD· 2 shared Yongjin ParkiD· 2 shared Alice E. StantoniD· 1 shared Amauche Emenari· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersNeuroscience

Li‐Huei TsaiORCID

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4 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 15, 2026

Expansion Revealing of Pathology Resolves Nanostructures Associated with Inflammatory Phenotypes in COVID-19 Decedent Human Brain Tissue

Alice E. Stanton, Jinyoung Kang, Joel Blanchard…·Li‐Huei Tsai

The paper introduces ExRPath and 15ExMPath techniques to expand human brain tissue for nanostructure analysis, revealing amyloid nanoclusters associated with SARS-CoV-2 in COVID-19 patients.

DOI 10.64898/2026.05.14.725177

humanimaging

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NeurosciencebioRxivPreprintApr 21, 2022

Single-cell mosaicism analysis reveals cell-type-specific somatic mutational burden in Alzheimer's Dementia

Maria Kousi, Carles A. Boix, Yongjin Park…·M Kellis

This study analyzes somatic mosaicism in Alzheimer's Dementia using single-cell data, finding increased mutational burden in specific cell types and genes associated with disease processes.

7 citations

humanscRNA-seq

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GenomicsbioRxivPreprintJan 21, 2021

Single-cell deconvolution of 3,000 post-mortem brain samples for eQTL and GWAS dissection in mental disorders

Yongjin Park, Liang He, José Dávila-Velderrain…·M Kellis

The paper deconvolves 3,387 post-mortem brain samples using SPLITR to identify cell-type-specific eQTLs and genetic effects in mental disorders.

11 citations

humanbulk RNA-seq

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NeurosciencebioRxivPreprintMay 12, 2020

Probing the functions of microglial cyclin-dependent kinase 5 under physiological and pathological conditions

Zhuyu Peng, Wen‐Chin Huang, Maggie Chen…·Li‐Huei Tsai

This study investigates the role of Cdk5 in microglia under physiological and pathological conditions, finding transcriptional changes but minimal effects on morphology and behavior.

DOI 10.1101/2020.05.12.090605

mousebulk RNA-seq

𝕏 PostBluesky