Ivy S. Samuels

This study shows that inhibiting FATP2 improves glucose tolerance via α-cell GLP-1 secretion and β-cell insulin release in diabetic mice.

This study uses a POLG deficiency model to show that mtDNA mutations cause retinal degeneration through impaired mitochondrial function and accelerated aging.

This study shows that reducing Glut1 in retinal neurons, but not the RPE, reduces polyol accumulation and prevents early diabetic retinopathy features in mice.