Author

Mainak Guharoy

Vrije Universiteit BrusselORCID 0000-0003-1354-2872Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Péter TompaiD· 2 shared Tamás LázáriD· 2 shared Wim VrankeniD· 2 shared A. Keith DunkeriD· 1 shared Ágnes TantosiD· 1 shared Alexander BotzkiiD· 1 shared Alexander Miguel MonzóniD· 1 shared Alok K. SharmaiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioinformatics

Péter TompaORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintDec 30, 2023

Integrating multiple omics levels using the human protein complexome as a framework, a multi-omics study of inborn errors of metabolism

Mainak Guharoy, Isabelle Adant, Matthew Bird…·Bart Ghesquiere

This study integrates proteomics, transcriptomics, and metabolomics data from IEM patients to identify perturbed protein complexes and pathways, highlighting mitochondrial oxidative phosphorylation and histone acetylation dysregulation.

DOI 10.1101/2023.12.30.573613

humanproteomics

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BioinformaticsNature MethodsPeer-reviewedApr 19, 2021

Critical Assessment of Protein Intrinsic Disorder Prediction

Marco Necci, Damiano Piovesan, CAID Predictors…·Silvio C. E. Tosatto

The paper evaluates 43 methods for predicting intrinsically disordered regions and binding regions in proteins, finding that deep learning methods outperform older physicochemical approaches but binding prediction remains challenging.

343 citationstop 1%

protein sequencedeep learning

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BioinformaticsBiophysical JournalPeer-reviewedMay 20, 2020

Distance-based metrics for comparing conformational ensembles of intrinsically disordered proteins

Tamás Lázár, Mainak Guharoy, Wim Vranken…·Péter Tompa

The paper introduces superimposition-free metrics to compare conformational ensembles of intrinsically disordered proteins by analyzing residue-residue distance distributions.

34 citations

protein structurestatistical model

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