Author

Josbert M. Metselaar

Universitätsklinikum AachenORCID 0000-0003-1360-0112Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Alexandros Marios SofiasiD· 2 shared Sara ElsafyiD· 2 shared Twan LammersiD· 2 shared Alessandro MottaiD· 1 shared Alessia Nucci· 1 shared Ben PeacockiD· 1 shared Eva Miriam BuhliD· 1 shared Fabian M. KiesslingiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPharmacology & Toxicology

Alexandros Marios SofiasORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintOct 22, 2026

Lipid nanoparticle shape and morphology determine the magnitude and duration of mRNA transfection

Sara Elsafy, Martin Dulle, Saba Shahzad…·Alexandros Marios Sofias

This study shows that LNP shape and morphology affect mRNA transfection efficiency and duration, with non-spherical LNPs showing higher expression despite similar uptake to spherical ones.

DOI 10.64898/2026.10.18.759824

experimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintSep 14, 2026

Nanoparticle size governs engagement with myeloid cells and hitchhiking to hematopoietic organs in myeloproliferative neoplasms

Sara Elsafy, Shiva Khorshid, Alessia Nucci…·Alexandros Marios Sofias

This study shows that nanoparticle size affects their uptake by myeloid cells and delivery to hematopoietic organs in myeloproliferative neoplasms.

DOI 10.64898/2026.09.07.749819

mouseexperimental assay

𝕏 PostBluesky