Author

Alessandro Motta

Universitätsklinikum AachenORCID 0000-0002-0113-4938Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Alessia Nucci· 2 shared Alexandros Marios SofiasiD· 2 shared Fabian M. KiesslingiD· 2 shared Federica De LorenziiD· 2 shared Jelena Lazarevic· 2 shared Julian BaumeisteriD· 2 shared Marcelo A. S. ToledoiD· 2 shared Margherita VieriiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Alessia Nucci

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Nanoparticle size governs engagement with myeloid cells and hitchhiking to hematopoietic organs in myeloproliferative neoplasms

Sara Elsafy, Shiva Khorshid, Alessia Nucci, Federica De Lorenzi, Alessandro Motta, Margherita Vieri, Jelena Lazarevic, Mithuoshni Arullmoli, Julian Baumeister, Nicolas Chatain, Eva Miriam Buhl, Fabian M. Kiessling, Twan Lammers, Steffen Koschmieder, Josbert M. Metselaar, , Alexandros Marios Sofias

This study shows that nanoparticle size affects their uptake by myeloid cells and delivery to hematopoietic organs in myeloproliferative neoplasms.

bioRxiv · Sep 14, 2026 · PreprintCancer Biology

Melatonin nanoparticles inhibit mutant hematopoiesis and restore bone marrow architecture in myeloproliferative neoplasms

Siddharth Gupta, Alessandro Motta, Sara Elsafy, Shiva Khorshid, Alessia Nucci, Vishrutha Sampath, Ananya Bhattacharjee, Margherita Vieri, Kathrin Olschok, Kristina Pannen, Jelena Lazarevic, Maria Jimena Rodriguez, Patrick Weiand, Venkatakrishnan Hariharan, Cristina Baquero López, , Nicolas Chatain

This study shows that melatonin nanoparticles reduce myeloproliferative neoplasm symptoms by targeting metabolic, inflammatory, and fibrotic pathways.

bioRxiv · Aug 31, 2026 · PreprintCancer Biology