Sudeshna Roy Chowdhury

The paper shows that Snx3 and SNX-BARs form hybrid endosomal coats in vivo, which have greater membrane scaffolding activity than homogeneous coats and allow for adaptable cargo sorting.

This study investigates how Vps5 and Vps17 SNX-BAR proteins assemble with Retromer, revealing a PL motif in Vps5 that binds Vps29 and is essential for membrane tubule association and cargo recycling.