Andreas Mayer

This study identifies Gyp6 as a GAP that regulates Ypt7 activity through Retromer to coordinate endosomal carrier formation in yeast.

The paper investigates how acidocalcisome-like vacuoles regulate cytosolic phosphate levels through polyphosphate synthesis and feedback mechanisms.

The paper identifies CROP2 as a Retriever-WIPI2 complex involved in exporting β1-Integrin from endosomes to the plasma membrane, distinct from the CROP complex.

The paper shows that Snx3 and SNX-BARs form hybrid endosomal coats in vivo, which have greater membrane scaffolding activity than homogeneous coats and allow for adaptable cargo sorting.

The paper uses 18O-water labeling to study phosphate group dynamics in inositol phosphates across species, revealing distinct pools with different cycling behaviors.

This study investigates how Vps5 and Vps17 SNX-BAR proteins assemble with Retromer, revealing a PL motif in Vps5 that binds Vps29 and is essential for membrane tubule association and cargo recycling.