Yu Xiao

The paper identifies hedgehog APN as a receptor for EriCoVs and shows convergent evolution in its utilization among merbecoviruses.

This study shows that targeted CNS radiotherapy disrupts DNA methylation and induces neuroinflammation through epigenetic changes in brain tissue and cerebral organoids.

This paper identifies DNA G-quadruplex accumulation as a universal mechanism driving aging across species by impairing epigenetic maintenance and promoting chromatin changes.

This paper introduces EpiTrace, a method using scATAC data to estimate cell age and lineage by analyzing clock-like chromatin accessibility, revealing insights into development and aging.

This study identifies epigenetic reprogramming defects in preeclampsia placenta that cause developmental delay and can be detected in serum cfDNA for early prediction.