Author

Inna Uliyakina

University of LisbonORCID 0000-0002-7091-2123Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Alfina A. SpecialeiD· 1 shared André GörgensiD· 1 shared Cláudia C. MendesiD· 1 shared CLIVE G. WILSONiD· 1 shared Daniel V. OlivençaiD· 1 shared Deborah C. I. GoberdhaniD· 1 shared Eberhard O. VoitiD· 1 shared Francisco Rodrigues PintoiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Alfina A. SpecialeORCID

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2 papers

Recent·Most cited

GAPDH controls extracellular vesicle biogenesis and enhances therapeutic potential of EVs in silencing the Huntingtin gene in mice via siRNA delivery

Ghulam Hassan Dar, Cláudia C. Mendes, Wei‐Li Kuan, Alfina A. Speciale, Mariana Conceição, André Görgens, Inna Uliyakina, Miguel J. Lobo, Wooi Fang Lim, Samir EL Andaloussi, Imre Mäger, Thomas C. Roberts, Roger A. Barker, Deborah C. I. Goberdhan, CLIVE G. WILSON, Matthew J. A. Wood

This study shows GAPDH facilitates EV biogenesis and enables efficient siRNA delivery to the brain, reducing huntingtin gene expression in a mouse model.

Nature Communications · Nov 18, 2021Peer-reviewedNeuroscience

A Mathematical Model of the Phosphoinositide Pathway

Daniel V. Olivença, Inna Uliyakina, Luís L. Fonseca, Margarida Duarte Amaral, Eberhard O. Voit, Francisco Rodrigues Pinto

The paper develops a computational model of the phosphoinositide pathway in mammalian cells, showing it replicates steady-state and dynamic phenomena and identifies key contributors to PI(4,5)P2 production.

Scientific Reports · Feb 26, 2018Peer-reviewedSystems Biology