Léopold Carron

The paper compares 3D chromatin organization across species to propose a layer cake model that refines the two compartments model by identifying distinct chromatin layers.

This paper investigates the distribution of disease-associated SNPs relative to 3D genome topological domains and finds that cancer risk loci are preferentially located at TAD borders.

This paper shows that H1 prevents H3K27me3 accumulation at telomeres and ITRs in Arabidopsis by restricting DNA accessibility to TRB proteins, while promoting PRC2 activity at genes.

Boost-HiC enhances long-range chromosomal contact maps by improving resolution using sparse data, enabling detection of Hi-C patterns with reduced sequencing depth.