Cyrille Favreau

The paper creates a detailed computational model of rat somatosensory cortex anatomy, including 4.2 million neurons and 14.2 billion synapses, and identifies limitations in connectivity prediction from morphology.

The paper develops a molecular model of the aging brain's metabolic system, identifies key disruptions, and proposes interventions to restore metabolic flexibility and neuronal function.

This study models blood flow dynamics in the rat somatosensory cortex, showing that astrocytic activity causes localized vasodilation and increased blood flow, particularly in capillaries.

The paper presents a full-scale in silico model of rat hippocampal CA1 integrating diverse experimental data and validates it through simulations of theta rhythm and other experiments.

The paper develops a computational model of mouse thalamoreticular microcircuitry to study sensory enhancement and sleep spindle properties, revealing mechanisms of network-level activity across brain states.