Author

Annabella Thomas

The University of MelbourneORCID 0000-0003-1416-3006Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Andreas StrasseriD· 2 shared Elizabeth LieschkeiD· 2 shared Lauren Whelan· 2 shared Aisling M. RossiD· 1 shared Alexandra L. GarnhamiD· 1 shared Allan Shuai HuangiD· 1 shared Amali CoorayiD· 1 shared Amar BalihodziciD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Andreas StrasserORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 2, 2026

Pre-existing levels of pro-survival proteins and induction of BCL-XL dictate cell fate after p53 activation

Allan Shuai Huang, Elizabeth Lieschke, Pedro L. Baldoni…·Andreas Strasser

The paper shows that pre-existing levels of pro-survival proteins and BCL-XL induction determine cell fate after p53 activation, with implications for cancer therapy.

DOI 10.64898/2026.07.01.735749

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyEMBO ReportsPeer-reviewedApr 30, 2025

Transcriptomic alterations including p53 pathway dysregulation prime DNMT3A mutant cells for transformation

Erin Lawrence, Amali Cooray, Andrew J. Kueh…·Marco J. Herold

This study shows DNMT3A mutations reduce DNA methylation and disrupt p53 pathway, increasing self-renewal and cancer risk in hematopoietic cells.

1 citation

mousebulk RNA-seq

𝕏 PostBluesky