Elisabeth Verboven

The paper uses EM-based spatial connectomics to reveal the 3D structure of the mouse liver's sympathetic network, showing it is a meshwork with exposed varicosities and diverse cellular contacts.

The paper maps enhancer gene regulatory networks (GRNs) in liver cell types and identifies TFs governing hepatocyte zonation states using multiomics and deep learning.

The paper identifies sex differences in bleeding risk and explores non-invasive vascular analysis in Alagille syndrome using mouse models and retinography.

This study shows that Jag1 deficiency in a mouse model of Alagille syndrome leads to impaired liver fibrosis due to defective T cell differentiation and hepatocyte maturation.