Emma Rachel Andersson

The paper uses EM-based spatial connectomics to reveal the 3D structure of the mouse liver's sympathetic network, showing it is a meshwork with exposed varicosities and diverse cellular contacts.

This study identifies SorCS2 as a regulator of Wnt signaling homeostasis by controlling Ror2 trafficking and signaling, with implications for neurodevelopment.

The paper uses in utero barcoding and single-cell transcriptomics to map clonal relationships in mouse mesoderm-derived tissues, revealing lineage relationships in liver and heart mesenchyme.

This study uses in utero lentiviral transduction to resolve clonal relationships and gene functions in developing mouse gut lineages, revealing distinct developmental patterns in mesenchyme and enteric nervous system.

The paper identifies a dynamic A-minor switch in RNA structures using NMR and cryo-EM, showing RNA dynamics influence function and revealing a new therapeutic target.

This study identifies CK1-mediated phosphorylation of NOTCH1 at S1970 as essential for its transcriptional activity and signaling in vivo.

The paper integrates single-cell, spatial, and clonal data to study cranial placode development and evolution, revealing continuous transcriptional landscapes and shared progenitors between placodes.

This study investigates how miR-34a interacts with its mRNA targets and how AGO2 modulates their binding affinity and structure, revealing structural determinants of repression efficacy.

The paper profiles clonal landscapes in mouse embryos to reveal spatial modulators of clonal fate biases using single-cell lineage tracing and clone2vec.

This study investigates the role of Jag1 in repressing Notch activation in lateral supporting cells and its impact on outer hair cell development in the cochlea using a mouse model of Alagille syndrome.

This study uses spatial transcriptomics and snRNA-seq to analyze host-pathogen interactions in P. berghei-infected mouse liver tissues, revealing changes in lipid metabolism and inflammatory responses.

The paper identifies sex differences in bleeding risk and explores non-invasive vascular analysis in Alagille syndrome using mouse models and retinography.

This study shows that Jag1 deficiency in a mouse model of Alagille syndrome leads to impaired liver fibrosis due to defective T cell differentiation and hepatocyte maturation.

This study uses spatial transcriptomics to analyze liver tissue, revealing zonation patterns and previously uncharacterized structures in the spatial transcriptome.

The paper introduces NEPTUNE, an in utero nanoinjection method to study gene function in mouse embryos, and shows that Sptbn2 silencing causes neural tube defects and embryo resorption.