Deborah J. Thompson

This study evaluates how polygenic risk scores can optimize screening programs to reduce premature deaths by tailoring screening ages based on genetic risk.

The paper releases and evaluates polygenic risk scores for 53 diseases and traits in the UK Biobank and shows they outperform existing scores.

This study assesses polygenicity and risk prediction using common variants across 14 cancers, finding varying numbers of susceptibility variants and risk score effectiveness.

This study combines genome-wide association data from four cancers to identify shared and novel genetic associations and pleiotropic effects.

The paper identifies genetic determinants of mosaic Y chromosome loss in blood and links it to genomic instability and non-haematological cancer risk.

This study identifies 78 genetic signals for male puberty timing using a large sample of men, revealing links to hair color and health outcomes.