Erika D. Eggers

The paper uses optogenetics to isolate the amacrine cell-OFF bipolar cell synapse and shows that D1R selectively reduces glycinergic inhibition.

This study investigates Ca2+ handling impairments in amacrine cells of diabetic mice using optogenetics and pharmacological blockers, finding altered kinetics in diabetic responses to L-type Ca2+ channel inhibition.

This study examines how blocking D4R and D1R receptors affects ERG signaling in diabetic rodents, finding that D4R blockade significantly alters light adaptation in diabetic retinas.

The paper identifies parallel neurodegenerative phenotypes in fibroblasts and iPSC-derived dopamine neurons from sporadic Parkinson's disease patients, revealing shared and distinct molecular and cellular alterations.

This study investigates how dopamine D1 and D4 receptors modulate light-evoked and spontaneous excitatory inputs to ON-sustained retinal ganglion cells in mice, finding that their activation reduces sensitivity to bright light.

This study shows that impaired light adaptation in diabetic mice is due to reduced dopamine D4 receptor sensitivity, not decreased receptor expression.