Natasha Oswal

The paper shows that declining mRNA synthesis capacity during aging reduces mRNA abundance, driving organismal aging, and that manipulating this decline affects healthspan and lifespan.

This study shows C. elegans uses temperature-sensing neurons to preemptively activate defenses against hydrogen peroxide, which becomes more reactive at higher temperatures.

The paper develops a hierarchical process model to link behavioral aging and lifespan in C. elegans, revealing two distinct but coupled physical declines that influence aging and longevity.