Author

Francesco A Servello

Northeastern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Javier ApfeldiD· 3 shared Matthias EderiD· 2 shared Nicholas StroustrupiD· 2 shared Olivier M. F. MartiniD· 2 shared Abigail L VogelaariD· 1 shared Anders LindbergiD· 1 shared Arjumand GhaziiD· 1 shared Francis R. G. AmritiD· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersNeuroscience

Javier ApfeldORCID

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3 papers

Recent·Most cited

Neuronal temperature perception induces specific defenses that enable C. elegans to cope with the enhanced reactivity of hydrogen peroxide at high temperature

Francesco A Servello, Rute Fernandes, Matthias Eder, Nathan Harris, Olivier M. F. Martin, Natasha Oswal, Anders Lindberg, Nohelly Derosiers, Piali Sengupta, Nicholas Stroustrup, Javier Apfeld

This study shows C. elegans uses temperature-sensing neurons to preemptively activate defenses against hydrogen peroxide, which becomes more reactive at higher temperatures.

eLife · Oct 13, 2022Peer-reviewedNeuroscience

C. elegans processes sensory information to choose between freeloading and self-defense strategies

Jodie A. Schiffer, Francesco A Servello, William R. Heath, Francis R. G. Amrit, Stephanie V. Stumbur, Matthias Eder, Olivier M. F. Martin, Sean B. Johnsen, Julian A. Stanley, Hannah Tam, Sarah J Brennan, Natalie G. McGowan, Abigail L Vogelaar, Yuyan Xu, William T. Serkin, , Javier Apfeld

The paper identifies a neuronal circuit in C. elegans that modulates hydrogen peroxide defenses based on sensory input and bacterial presence.

eLife · May 4, 2020Peer-reviewedNeuroscience

The heat shock transcription factor HSF-1 protects Caenorhabditis elegans from peroxide stress

Francesco A Servello, Javier Apfeld

This study shows HSF-1 protects C. elegans from oxidative stress through two distinct mechanisms depending on temperature conditions.

Translational Medicine of Aging · Jan 1, 2020Peer-reviewedGenetics