Genetic & Genomic MedicinemedRxivPreprint
Type 2 diabetes polygenic risk score demonstrates context-dependent effects and associations with type 2 diabetes-related risk factors and complications across diverse populations
4 citations
Author
Jack W. Pattee
University of MinnesotaORCID 0000-0003-1480-3157Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2022-2025 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship2 shared papersGenetic & Genomic Medicine
Ben Michael BrumptonORCID
Mutual co-authors in cluster
4 papers
Recent·Most cited
- Genetic & Genomic MedicineCirculationPeer-reviewed
Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
Florian Thibord, Derek M. Klarin, Jennifer A. Brody…·Nicholas L. Smith
This study identifies 135 genomic loci associated with venous thromboembolism risk through cross-ancestry GWAS and provides insights into biological pathways and potential therapeutic targets.
105 citationstop 1% - Systems BiologybioRxivPreprint
Power and precision: Evaluation and recommendations of quantitative trait analysis methods for RNA expression levels in the Hybrid Rat Diversity Panel
Jack W. Pattee, Lauren A. Vanderlinden, Spencer B. Mahaffey…·Laura M. Saba
The paper evaluates quantitative trait analysis methods for RNA expression in the HRDP to assess power and precision in identifying genetic variants associated with complex traits.
DOI 10.1101/2022.07.14.500105 - Genetic & Genomic MedicinemedRxivPreprint
Multi-ancestry GWAS deciphers genetic architecture of abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target
Tanmoy Roychowdhury, Derek M. Klarin, Michael G. Levin…·Scott M. Damrauer
This study identifies 144 genetic loci associated with abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target through Mendelian Randomization and pre-clinical validation.
9 citations