Author

Joseph John Provost

James Madison UniversityORCID 0000-0003-1487-1459Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Angela J. KaylliD· 2 shared Christopher BerndseniD· 2 shared Caroline Tuck· 1 shared Gabriel Rementeria· 1 shared Jackson R TesteriD· 1 shared Lisa GentileiD· 1 shared Renee St John· 1 shared Ruhi Rahman· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Angela J. KayllORCID

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2 papers

Recent·Most cited

BiochemistryActa Crystallographica Section D Structural BiologyPeer-reviewedJun 15, 2026

Molecular Architecture of the human Citrate Synthase-Malate Dehydrogenase 2 metabolon

Angela J. Kayll, Umanga Rupakheti, Renee St John…·Christopher Berndsen

The paper provides structural evidence for the human Citrate Synthase-Malate Dehydrogenase 2 metabolon and shows its transient nature and non-specific interaction site.

1 citation

humanstructural biology

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BiochemistrybioRxivPreprintJul 15, 2025

Structural and enzymatic divergence between human MDH isoforms underlies their specialized regulatory roles in metabolism

Christopher Berndsen, Angela J. Kayll, Ruhi Rahman…·Joseph John Provost

This study compares human MDH1 and MDH2 isoforms to show structural and enzymatic differences that explain their distinct regulatory roles in metabolism.

1 citation

humanproteomics

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