Molecular BiologyScientific ReportsPeer-reviewed
Proteome-wide landscape of solubility limits in a bacterial cell
Ádám Györkei, Lejla Daruka, Dávid Balogh…·Balázs Papp
The paper systematically investigates solubility limits of Escherichia coli proteins upon overexpression, revealing that most insoluble proteins aggregate after folding and that high disorder content and low surface stickiness correlate with solubility.
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