M. Irina Stefana

Expression of non-neuronal Tau in humans and mice

The paper confirms non-neuronal Tau expression in multiple tissues of humans and mice using validated antibodies and tissue microarrays.

Tau depletion in human neurons mitigates A beta-driven toxicity

This study shows that reducing tau in human neurons decreases A beta toxicity, supporting the role of tau in Alzheimer's disease mechanisms.

Validation of Tau Antibodies for Use in Western Blotting and Immunohistochemistry

This paper evaluates 53 Tau antibodies for Western blot and immunohistochemistry, identifying those with high specificity and sensitivity for detecting Tau, including low-level and modified forms.

Non-apoptotic caspase activation sustains ovarian somatic stem cell functions by modulating Hedgehog-signalling and autophagy.

This study shows non-apoptotic caspase activation modulates Hedgehog-signalling and autophagy in ovarian somatic stem cells, sustaining their function without inducing apoptosis.

Analysis of overlapping genetic association in type 1 and type 2 diabetes

This paper identifies four genetic regions associated with both type 1 and type 2 diabetes, with three showing opposite effect directions and one showing concordant effects.