Author
Justin Y. Kwan
National Institutes of HealthORCID 0000-0003-1558-4451Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2019-2025 · peak 1/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links4 papers
Recent·Most cited
- NeurosciencebioRxivPreprintDOI 10.64898/2025.12.29.696888
- NeuroscienceScience Translational MedicinePeer-reviewed
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD
Sahba Seddighi, Yue Andy Qi, Anna‐Leigh Brown…·Michael Emmerson Ward
The paper shows that loss of TDP-43 function leads to the expression of de novo proteins from mis-spliced mRNA transcripts in ALS/FTD.
189 citationstop 1% - NeuroscienceCommunications BiologyPeer-reviewed
Cell environment shapes TDP-43 function: implications in neuronal and muscle disease
Urša Šušnjar, Neva Škrabar, Anna‐Leigh Brown…·Emanuele Buratti
The paper compares TDP-43's transcriptional and splicing effects in muscle and neuronal cells, showing tissue-specific roles in disease.
58 citationstop 2% - GenomicsCell ReportsPeer-reviewed
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia
Oliver H. Tam, Nikolay V. Rozhkov, Regina Shaw…·John Ravits
The paper uses unsupervised machine learning to identify three molecular subtypes in ALS cortex samples, associated with oxidative stress, retrotransposon activation, and glial activation.
327 citationstop 1%