Won‐Kyung Ho

This study shows that Kv4.2 channels regulate baseline synaptic strength by inhibiting R-type calcium channels, with effects distinct from long-term potentiation.

The paper investigates how CA3 pyramidal cell excitability is regulated by mossy fiber and perforant pathway inputs, showing their role in sequence learning through bidirectional regulation of excitability and synaptic plasticity.

This study investigates how subthreshold depolarization enhances glutamate release via L-type Ca2+ channels and Ca2+-dependent signaling molecules.

The paper shows that burst firing in hippocampal granule cells is necessary for Hebbian LTP at lateral perforant path synapses, but not at medial perforant path synapses.

The paper investigates whether voltage-gated calcium channels (VGCCs) contribute to spontaneous glutamate release, finding that coupling distance and calmodulin influence this contribution in different synapses.

This study shows calbindin regulates Kv4.1 trafficking and neuronal excitability via CaMKII-dependent phosphorylation, linking Ca2+ buffering to neuronal function.

This study shows that Tg2576 mice exhibit impaired pattern separation linked to hyperexcitable dentate gyrus due to Kv4.1 downregulation, which is reversible with antioxidant treatment.

This study shows that Kv1.2 regulates hippocampal CA3 neuronal ensemble size and plasticity, contributing to pattern separation by preventing excessive synaptic changes.

This study identifies Kv4.1 as a key ion channel regulating low-frequency firing in mature dentate granule cells, essential for pattern separation.

This study shows that dendritic Na+ spikes are necessary for LTP at perforant path-granule cell synapses in rat hippocampal slices.