Author

Mariko Aoyagi Keller

Rutgers New Jersey Medical SchoolORCID 0000-0003-1586-2386Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Michinari NakamuraiD· 2 shared Andreas IvessaiD· 1 shared Hong Li AiD· 1 shared Peter J. RomanienkoiD· 1 shared Tong LiuiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

Michinari NakamuraORCID

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2 papers

Recent·Most cited

Cell BiologyJournal of the American Heart AssociationPeer-reviewedOct 28, 2025

Ketone Catabolism is Essential for Maintaining Normal Heart Function During Aging

Mariko Aoyagi Keller, Michinari Nakamura

This study shows that ketone catabolism is essential for maintaining heart function during aging, with ketone supplementation partially rescuing cardiac dysfunction in mice lacking the SCOT enzyme.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintJan 14, 2025

KAT6A acetylation drives metabolic adaptation to mediate cellular growth and mitochondrial metabolism through AMPK interaction

Mariko Aoyagi Keller, Andreas Ivessa, Tong Liu…·Michinari Nakamura

This study shows KAT6A acetylation at K816 enhances AMPK interaction, promoting mitochondrial function and protecting against cardiac hypertrophy in mice.

2 citations

mousebulk RNA-seq

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