Author

Robert G. Griffin

Massachusetts Institute of TechnologyORCID 0000-0003-1589-832XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Christopher G. WilliamsiD· 1 shared Dev ThackeriD· 1 shared Fang QianiD· 1 shared Leonard J. MuelleriD· 1 shared Paul H. WeinrebiD· 1 shared Ravi Shankar PalaniiD· 1 shared Robert SilversiD· 1 shared Sara Snogerup LinseiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

Christopher G. WilliamsORCID

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1 paper

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedDec 22, 2025

Aducanumab Binding to Aβ1-42 Fibrils Alters Dynamics of the N-Terminal Tail While Preserving the Fibril Core

Ravi Shankar Palani, Christopher G. Williams, Dev Thacker…·Robert G. Griffin

This paper investigates how aducanumab binds to Aβ1-42 fibrils, showing it preserves the fibril core structure while altering N-terminal dynamics and reducing secondary nucleation.

5 citations

humanexperimental assay

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