Author

Daniel Stone

Fred Hutch Cancer CenterORCID 0000-0003-1619-7541Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Keith R. JeromeiD· 3 shared Anoria K. Haick· 2 shared Laurence Stensland· 2 shared Lindsay M. KlouseriD· 2 shared Martine AubertiD· 2 shared Michelle A. LoprienoiD· 2 shared Pavitra RoychoudhuryiD· 2 shared Ailyn C. Pérez-OsorioiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersMolecular Biology

Keith R. JeromeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJan 21, 2025

Minimization of gene editing off-target effects by tissue restriction of expression

Nam‐Gyun Kim, Martine Aubert, Anoria K. Haick…·Keith R. Jerome

This study shows that restricting meganuclease expression to specific tissues reduces off-target gene editing in vivo.

3 citations

mouseDNA methylation

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NeurosciencebioRxivPreprintSep 23, 2022

AAV-delivered gene editing for latent genital or orofacial herpes simplex virus infection reduces ganglionic viral load and minimizes subsequent viral shedding in mice

Martine Aubert, Anoria K. Haick, Daniel E. Strongin…·Keith R. Jerome

This study shows that AAV-delivered gene editing reduces latent HSV DNA in mice and decreases viral shedding, with some toxicity observed at high doses.

2 citations

mouseexperimental assay

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BioinformaticsBMC BiologyPeer-reviewedJul 11, 2018

Viral diversity is an obligate consideration in CRISPR/Cas9 designs for HIV cure

Pavitra Roychoudhury, Harshana S. De Silva Feelixge, Daniel B. Reeves…·Keith R. Jerome

This paper identifies highly-conserved CRISPR guide RNAs for HIV cure and models the impact of viral diversity on therapeutic success.

31 citations

humanCRISPR screen

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