Author

Laurence Stensland

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Keith R. JeromeiD· 4 shared Anoria K. Haick· 3 shared Lindsay M. KlouseriD· 3 shared Daniel StoneiD· 2 shared Hong Jian XieiD· 2 shared Marius WalteriD· 2 shared Martine AubertiD· 2 shared Michelle A. LoprienoiD· 2 shared

Activity by Year

2022-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

Keith R. JeromeORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Herpes simplex virus 1 strain 17+ with R2 mutation in UL37 has residual retrograde transport

Marius Walter, Anoria K. Haick, Paola A Massa, Lindsay M. Klouser, Laurence Stensland, Tracy K. Santo, Hong Jian Xie, Keith R. Jerome

This study shows that the R2 mutation in UL37 of HSV-1 strain 17+ only partially blocks retrograde transport, allowing latency and reactivation in mouse models.

Microbiology Spectrum · Dec 3, 2025Peer-reviewedMicrobiology

Pooled CAR-T screening in nonhuman primates identifies designs with enhanced proliferation, trafficking, and persistence

Lucy H. Maynard, Eric J. Cavanaugh, Haiying Zhu, Carly E. Starke, Sarah M. Doherty, Teresa Einhaus, Ailyn Perez, Laurence Stensland, Michelle Hoffman, Veronica Nelson, Sarah Herrin, Chad Littlewood, Kaycee Camou, Erica Wilson, Christopher Wessel, , Christopher W. Peterson

This study screens CAR-T designs in nonhuman primates and identifies MyD88-CD40 costimulatory domains as superior for proliferation, trafficking, and persistence.

bioRxiv · Mar 5, 2025 · PreprintImmunology

Minimization of gene editing off-target effects by tissue restriction of expression

Nam‐Gyun Kim, Martine Aubert, Anoria K. Haick, Paola A Massa, Michelle A. Loprieno, Marius Walter, Hyeong Geon Kim, B. Ethan Nunley, Hong Jian Xie, Laurence Stensland, Lindsay M. Klouser, Ailyn C. Pérez-Osorio, Daniel Stone, Pavitra Roychoudhury, Keith R. Jerome

This study shows that restricting meganuclease expression to specific tissues reduces off-target gene editing in vivo.

bioRxiv · Jan 21, 2025 · PreprintMolecular Biology

AAV-delivered gene editing for latent genital or orofacial herpes simplex virus infection reduces ganglionic viral load and minimizes subsequent viral shedding in mice

Martine Aubert, Anoria K. Haick, Daniel E. Strongin, Lindsay M. Klouser, Michelle A. Loprieno, Laurence Stensland, Tracy K. Santo, Meei-Li W. Huang, Ollivier Hyrien, Daniel Stone, Keith R. Jerome

This study shows that AAV-delivered gene editing reduces latent HSV DNA in mice and decreases viral shedding, with some toxicity observed at high doses.

bioRxiv · Sep 23, 2022 · PreprintNeuroscience