Mark Chernyshev

The paper presents a high-resolution analysis of human IGH germline gene diversity across 2,486 individuals from 25 global populations, revealing population-specific patterns and disease-linked haplotypes.

The paper shows that genetic variation in human immunoglobulin genes affects antibody responses to influenza HA, informing vaccine design to cover diverse populations.

This paper introduces CHMMAIRRa, a hidden Markov model to detect PCR chimeras in AIRR-seq data, incorporating somatic hypermutation and germline references.

This paper introduces two methods for denoising long-read amplicon sequencing data, achieving higher accuracy than existing methods.