Author

Devin N. Fachko

Oregon Health & Science UniversityORCID 0000-0003-1646-8102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:CRISPR screen· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Rebecca L. SkalskyiD· 3 shared Andrew Pham· 1 shared Jennifer MitchelliD· 1 shared Kelley Bastin· 1 shared Luke Slind· 1 shared Meaghan H. HancockiD· 1 shared Nicole L. DigginsiD· 1 shared Nikita S. Ivanov· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersMolecular Biology

Rebecca L. SkalskyORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 19, 2026

Human cytomegalovirus microRNAs target the Wnt signaling protein Dishevelled 3 to promote efficient reactivation in CD34+ hematopoietic progenitor cells

Nicole L. Diggins, Luke Slind, Jennifer Mitchell…·Meaghan H. Hancock

This study shows that HCMV miRNAs miR-US5-2 and miR-US25-2 downregulate Dvl3 during latency to enable efficient reactivation in CD34+ HPCs.

DOI 10.64898/2026.10.18.759990

humanexperimental assay

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Molecular BiologyPLoS PathogensPeer-reviewedJun 17, 2024

MicroRNA-focused CRISPR/Cas9 Screen Identifies miR-142 as a Key Regulator of Epstein-Barr Virus Reactivation

Yan Chen, Rodney P. Kincaid, Kelley Bastin…·Rebecca L. Skalsky

The paper identifies miR-142 as a regulator of EBV reactivation through CRISPR/Cas9 screening and shows it suppresses SOS1/Ras/Raf/Mek/Erk signaling initiated by the BCR.

13 citations

humanCRISPR screen

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Molecular BiologybioRxivPreprintNov 12, 2019

B Cell Receptor-Responsive miR-141 and viral miR-BART9 promote Epstein-Barr Virus Reactivation Through FOXO3 Inhibition

Yan Chen, Devin N. Fachko, Nikita S. Ivanov, Rebecca L. Skalsky

The paper identifies miR-141 and EBV miR-BART9 as regulators of B cell reactivation through FOXO3 inhibition, linking BCR signaling to lytic replication in EBV.

1 citation

humanexperimental assay

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