Yan Chen

This study identifies LCA's mechanism of action through TULP3-sirtuin-v-ATPase-AMPK pathway to activate AMPK and extend lifespan in model organisms.

The paper identifies miR-142 as a regulator of EBV reactivation through CRISPR/Cas9 screening and shows it suppresses SOS1/Ras/Raf/Mek/Erk signaling initiated by the BCR.