Jennifer Mitchell

This study shows that HCMV miRNAs miR-US5-2 and miR-US25-2 downregulate Dvl3 during latency to enable efficient reactivation in CD34+ HPCs.

This paper shows that HCMV's UL22A protein is essential for reactivation from latency in CD34+ hematopoietic progenitor cells, with tyrosine residues critical for this process, but RANTES neutralization does not fully restore reactivation.

This study identifies UL78 as a nuclear-localized GPCR essential for HCMV reactivation from latency in CD34+ HPCs, showing its Gi coupling and interactome involvement in nuclear processes.

This study shows that HCMV miRNAs downregulate Akt to promote reactivation from latency in CD34+ cells and humanized mice.