NeurosciencePLoS BiologyPeer-reviewed
FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provides a target for Pink1 phosphorylation in vivo
Álvaro Sánchez-Martínez, Aitor Martinez, Alexander J. Whitworth
The paper shows FBXO7/ntc and USP30 regulate basal mitophagy through opposing ubiquitination and deubiquitination mechanisms, with implications for Parkinson's disease therapy.
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