Author

Madeleine J. Twyning

University of CambridgeORCID 0000-0003-0656-9989Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander J. WhitworthiD· 2 shared Álvaro Sánchez-MartíneziD· 2 shared Aitor MartineziD· 1 shared Ana Terriente-FélixiD· 1 shared Chun‐Hong CheniD· 1 shared Heather MortiboysiD· 1 shared Hiran A. PragiD· 1 shared Jake T. PickeringiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Alexander J. WhitworthORCID

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2 papers

Recent·Most cited

NeuroscienceLife Science AlliancePeer-reviewedJun 21, 2024

Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction in C9orf72 ALS/FTD in vivo models and patient iNeurons

Wing Hei Au, Leonor Miller‐Fleming, Álvaro Sánchez-Martínez…·Alexander J. Whitworth

This study shows that activating the Keap1/Nrf2 pathway reduces mitochondrial dysfunction and motor deficits in C9orf72 ALS/FTD models and patient-derived neurons.

25 citationstop 2%

Drosophilahuman

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NeurosciencebioRxivPreprintMay 14, 2023

Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models

Aitor Martinez, Álvaro Sánchez-Martínez, Jake T. Pickering…·Alexander J. Whitworth

1 citation

Drosophilaexperimental assay

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