Author

Jennifer N. Dines

University of WashingtonORCID 0000-0003-1649-2006Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:variant effect prediction· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Douglas M. FowleriD· 2 shared Alexander Wahl· 1 shared André FrankeiD· 1 shared Arineh Khechaduri· 1 shared Bernd BokemeyeriD· 1 shared Beth MartiniD· 1 shared Britt A. JohnsoniD· 1 shared Bryan Howie· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersGenetics

Douglas M. FowlerORCID

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3 papers

Recent·Most cited

ImmunologyJournal of Crohn s and ColitisPeer-reviewedMar 13, 2025

Antigen-driven expansion of public clonal T cell populations in inflammatory bowel diseases

Mitchell W. Pesesky, Ramit Bharanikumar, Lionel Le Bourhis…·Matthieu Allez

The paper identifies public TCRB sequences expanded in CD or UC, associated with HLA alleles and antigen-specific immune responses, showing differential expansion in CD compared to UC and healthy controls.

19 citationstop 1%

humanCITE-seq

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GeneticsbioRxivPreprintFeb 13, 2024

A missense variant effect map for the human tumour suppressor protein CHK2

Marinella Gebbia, Daniel Zimmerman, Rosanna Jiang…·Frederick P. Roth

The paper creates a functional map of all possible missense variants in CHK2 to assess their impact on cancer risk.

1 citation

humanexperimental assay

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GeneticsNature GeneticsPeer-reviewedMay 20, 2018

Multiplex Assessment of Protein Variant Abundance by Massively Parallel Sequencing

Kenneth A. Matreyek, Lea M. Starita, Jason J. Stephany…·Douglas M. Fowler

This paper introduces VAMP-seq, a method to assess the abundance of protein variants, and identifies pathogenic variants in PTEN and TPMT.

449 citationstop 1%

humanproteomics

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