Eric Féraille

This study shows high-salt diets increase urinary cortisol and decrease plasma FGF23, revealing a novel endocrine interaction with implications for bone, kidney, and cardiovascular health.

This study shows that a low-salt diet increases claudin-3 expression in mice, which reduces paracellular sodium permeability, and claudin-3-deficient mice adapt by upregulating other claudins and ENaC to maintain sodium balance.

This study identifies 11beta-HSD1 as a driver of myofibroblast differentiation in CKD, showing its inhibition reduces fibrosis and improves renal function.

This study identifies the outer stripe of the outer medulla as the most metabolically active and injured region in the kidney during ischemia-reperfusion injury, showing propofol exacerbates this damage through mitochondrial and fatty acid oxidation impairment.